Biophysical induction of vascular smooth muscle cell podosomes.
Vascular smooth muscle cell (VSMC) migration and matrix degradation occurs with intimal hyperplasia associated with atherosclerosis, vascular injury, and restenosis.One proposed mechanism by which VSMCs degrade matrix phi mu dad shirt is through the use of podosomes, transient actin-based structures that are thought to play a role in extracellular